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Fritillaria Bulb
Fritillaria Bulb
浙貝(貝母)大
Market name:浙貝(貝母)大
Photo location:Museum of Materia Medica, Inst. of Nat. Med.
TMPW No.:11361
Fritillaria thunbergii
Plant name:Fritillaria thunbergii
Photo location:Tokyo, Japan
Photo date:1997
Photographer:K. Komatsu

Synonym  
Latin name Fritillariae Bulbus
Botanical source: Family name Liliaceae
Botanical source: Plant name Fritillaria verticillata var. thunbergii Baker
Part used Bulb
Empirical criteria for quality selection Good one is small. It has white outside and tannish flesh side (NI).
Constituents Steroidal alkaloids:
[F. thunbergii]: Fritilline, Fritillarine, Verticine (= Peimine), Verticilline, Apoverticine, Peiminoside, Peimisine, Peimiphine, Peimidine, Peimitidine;
[F. verticillata]: Fritilline A, Fritilline B, Peimisine, Verticilline, Verticine (= Peimine), Peiminoside, Verticinone (= Fritillarine = Peiminine), Isoverticine;
[F. roylei]: Peimidine, Peimiphine, Peimitidine, Peimisine, Verticine (= Peimine)
Pharmacological effects Hypotensive (peimine, peiminoside).
Indications As an antitussive, expectorant and for draining pus, it is applied to relieve heat, laryngitis, dazzling, cough and thirst. Zhebeimu (浙貝 in JP) has stronger effects in removing heat and resolving phlegm than that of chuanbeimu (川貝 in JP) . Zhebeimu (浙貝 in JP) is applied to treat cough with heat and persisting sputum.
Diseases Cough, Sore throat, Few sputum, Expectoration of sputum, Cervical lymphadenopathy, Chest pain, Feeling of pressure in the chest, Lung suppurations, Subcutaneous nodule, Pyogenic dermatosis
Formulas karokijitsuto , gedaishimotsutokami , sammotsuhakusan , jiinshihoto , seihaito , tokibaimokujinganryo
Meridian tropism Heart, Lung
Property Slightly cold
Flavor Sweet, Slightly bitter
Classification in "Shen-non Ben-cao Jing" Middle
TCM: Classification Phlegm-resolving drugs with cold properties
TCM: Medicinal effects To remove heat and resolve phlegm, to ease the mind, and to reduce nodulation.
Used for cough caused by wind heat, dryness heat or phlegm heat, lung abscess, mastitis, cervical tuberculous lymphadenitis and sores.
Remarks Listed in the Japanese Pharmacopoeia 18th ed.
References NI: N. Isshiki, Methods of Quality Evaluation and Preparation of Wakan-yaku, Tohodo Shoten, Tokyo, 1987.
DNA sequences of medicinal plants
Gene Region
Nuclear Chloroplast Mitochondria
Botanical source: Plant name 5Ss 18S ITS1 5.8S ITS2 26S others trnH-psbA matK trnK trnK-rps16 trnT-L trnL trnL-F rbcL rpoC1 ndhF others
Fritillaria verticillata var. thunbergii Baker
 

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Section of Pharmacognosy,
Division of Medicinal Resources,
Department of Research and Development,
Institute of Natural Medicine,
University of Toyama
2630 Sugitani, Toyama 930-0194 Japan
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